产物概况：
Purity: Fe, Al, Ti, Na < 10 ug/g total
Pore Diameter: 120 A
Pore Volume: 0.7 ml/g
Surface Area: 230 m2/g, 120 m2/ml
Particle size: 1.5, 3, 5, 7 and 10 µm
Exsil Pure C18MS
The pharmaceutical industry is a major user of LC-MS and their interest centres on basic compounds. The MS sensitivity is increased by operating at high organic content and this has led to an interest in operation at neutral and high pH which increases the retention of bases allowing the use of high organic content mobile phases. Stable products with low bleed rates and capable of giving high effi🦹ciency separations are required. In addition, products should be capable of operating with volatile buffers and maximising the retention of bases.
Conventional reversed phase media provide low bleed and good stability but the peak shape of bases at higher pHജ can be a problem. Polar embedded phases give better peak shape at neutral and high pH but often suffer from bleed. They invariably give lower retention than standard reversed phase media and need lower organic content mobile phases which are opposite to the customer requirements.
• High Polarity: 🐷 Different selectivity to current phases.
• High Base Retention: Uses 🌄high % organic: aids MS detection
• Compatible with MS buffers: &n𒀰bsp; &๊nbsp; Good with volatile buffers
• High Stability: 🍒 No embedded phase to limit stability
• Low MS bleed: &nb🌟sp; &𝓡nbsp; Aids MS Detection
• Acids, Bases, Chelate🐼s: ꦏ All the benefits of pure silica
• 100% Aqueous Stability: Resists phase collapse
Exsil Pure RP18
In recent years, high purity silicas bonded with monofunctional C18 and fully end capped have become the standard phase for difficult analyses. The success of this approach is eviden𝄹ced by a large number of these phases available. They do have some drawbacks; these being primarily tailing with some bases at neutral pH and a high degree of similarity in sel🍰ectivity. Despite these drawbacks, such phases are popular and we have produced such a phase on Exsil Pure.
• High Purity Silica: 𝔉; Good chromatography of ꩵacids and bases
• High efficiency: &nbs🌠p; Typically 85-105,000 plates/m for 5mm
• Cost effective: &𝔍nbsp; ෴ High performance at low cost
• Reproducible: Typical Exmere reliabilit🌟y
• High pH Stability: pH 12 clean in situ
Exsil Pure Paragon C18
Exsil reversed phase silicas have an outstanding record for reproducibility and are available in a wide range that offers alternative selectivities to conventional reversed phase media. However due to a continuing demand for a phase which combines conventional selectivity with Exsil performance we have drawn on our experience of over 20 years of phase development to produce.
• H꧙igh Purity ꩲSilica: Good chromatography of acids, bases and neutrals
• High efficiency: &🌟nbsp; Typically 100 000 plates/m for 5µm
• Cost effective: High perfor🦂mance at lower cost
• Reproducible: &n🐈bsp; &n🎃bsp; Typical Exmere reliability
• Conventional selectivity: &nbꦗsp; Direct alternative to many R♏P phases
• 120A in 3,5 and 10μm: &nb🔜sp; &nღbsp; Ideal for small to medium sized molecules.
• Carbon loading: &nℱbsp; Very high alkyl loaded (pH stable up to 11)
